Premium
Biochemical nutritional parameters in patients suffering from head and neck cancer after the administration of nutritional support. Preliminary study.
Author(s) -
Casbarien Octavio,
Cresta Pablo,
Silva Carolina,
Feliu Maria Susana,
Badia A,
DELGADO N LÓPEZ,
Perman Mario,
Navigante Alfredo,
Slobodianik Nora
Publication year - 2013
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.27.1_supplement.864.3
Subject(s) - radial immunodiffusion , medicine , transferrin , head and neck cancer , gastroenterology , cancer , transthyretin , immunology , antibody
The evaluation of nutritional status, through biochemical parameters, in a subgroup of these patients, before and after oral intake of a nutritional supplement. Seven adult patients, were attended in the A. Roffo Institute, with local advanced head and neck cancer, underwent therapy with chemoradiotherapy that completed oral intake of a nutritional supplement, during 60 days (Supportan ® , Fresenius‐Kabi ). The supplement provides 500Kcal/day, P%27, F%40 (2 g EPA provided by fish oil, MCT and vegetal oils) and 33% of carbohydrates. Blood samples were collected from patients before(To) and after (Tf) the oral administration of the supplement plus habitual diet. Specific serum protein fractions:TTR, transferrin, C3c, C4c, Cp, Hp and PCR were measured by single radial immunodiffusion technique(Biocientífica SA, Argentina and Binding Site, UK). Results Tf vs To (mg/dl), expressed as X (SD) were:TTR:21.1(8.9) vs 22.9(7.3); Transferrin:188.9(36.1) vs 207.3 (20.9) ;C3c :122.6(24.9) vs 122.5(52.3);C4c:37.5( 7.4) vs 38.9 (11.1); Cp: 40.0 (6.7) vs 36.1(11.7), Hp: 334.0(194.2) vs 245.6(103.9); PCR : 1.4( 0.3) vs 1.6(2.1). No differences between Tf and To were observed. Data suggest that the administration of this oral supplement was useful to maintain the initial biochemical nutritional profile. Supported by UBA( 20020100100044)