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Harmful Relationship between Alcohol Consumption and Brachial Ankle Pulse Wave Velocity : No Favorable Zone for Vascular Damages
Author(s) -
Kim Mi Kyung,
Shin Jinho,
Kweon SunSeong,
Shin Dong Hoon,
Lee YoungHoon,
Chun ByungYeol,
Choi Bo Youl
Publication year - 2013
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.27.1_supplement.848.12
Subject(s) - arterial stiffness , medicine , alcohol consumption , cardiology , pulse wave velocity , alcohol , brachial artery , blood pressure , chemistry , biochemistry
Arterial stiffness and increased intima‐media wall thickness is one of the biggest predictors of cardiovascular disease. We evaluated whether brachial‐ankle pulse wave velocity (baPWV) and common carotid artery intima‐media wall thickness (CCA‐IMT) are correlated with alcohol consumption among men and women aged 40 years and over in a rural area of Korea(2,216 men and 3,428 women). The baPWV was positively correlated with alcohol consumption in men (p for trend <0.0001), but not in women. Age (middle‐aged or elderly) modified the effect of alcohol consumption on PWV and the relation was more evident in the elderly. There was no favorable zone of alcohol consumption in relation to baPWV. CCA‐IMT was likely to decrease with alcohol consumption in both men and women and a linearly decreasing trend for CCA‐IMT with alcohol consumption was found for women, but there was no statistically difference across alcohol consumption groups. In conclusion, there may be not only a linear harmful relationship between alcohol consumption and the arterial stiffness but also neutral effect of alcohol on carotid atherosclerosis without any favorable zone. The effect of alcohol on arterial stiffness may be stronger among elderly men.