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A prudent diet attenuates lung function decline in cigarette smokers
Author(s) -
Tang Wenbo,
Guertin KA,
Arnold KB,
Hartline JA,
Minasian LM,
Lippman SM,
Klein E,
Cassano PA
Publication year - 2013
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.27.1_supplement.847.17
Subject(s) - lung function , medicine , confounding , western diet , food frequency questionnaire , nutrient , demography , physiology , lung , biology , obesity , ecology , sociology
Background Most previous studies of diet and lung function focus on individual nutrients and/or foods. Dietary pattern analysis is a strong alternative approach, but very few studies examine the dietary pattern—lung function decline association. Methods The association between dietary patterns and decline of forced expiratory volume in 1 s (FEV 1 ) was investigated in 2,560 male adults. Dietary patterns were derived from food frequency data using principal component analysis, and linear mixed‐effects models examined these patterns with FEV 1 decline over ~3 years, adjusting for confounders. Given the importance of smoking, dietary pattern × smoking interactions were tested. Results A more prudent pattern (higher intake of fruits, vegetables and whole grains) was associated with a slower decline in FEV 1 in smokers only (top vs. bottom tertile of pattern: +37.8 mL/y; trend P interaction = 0.0008). A more Western pattern (higher intake of meat, potatoes and snacks) was associated with a lower FEV 1 at study baseline (top vs. bottom quintile: −162.4 mL; P for trend = 0.001), but not with FEV 1 decline either overall or by smoking. Conclusions In males, a prudent dietary pattern was associated with a slower decline in lung function in smokers only, and a Western dietary pattern was associated with lower levels of lung function, but not change over time. Grant Funding Source : NHLBI R01HL071022 (PAC), and, in part, NCI/DCP CA37429, NCCAM.