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Inflammation and Nutritional Science for Programs/Policies: Interpretation of Research Evidence
Author(s) -
Ashour Fayrouz Sakr,
Raiten Daniel,
Ross Catharine,
Meydani Simin
Publication year - 2013
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.27.1_supplement.846.16
Subject(s) - timeline , function (biology) , extant taxon , interpretation (philosophy) , engineering ethics , medicine , psychology , biology , computer science , engineering , geography , programming language , archaeology , evolutionary biology
The Inflammation and Nutritional Science for Programs/Policies and Interpretation of Research Evidence (INSPIRE) project is intended to develop principles and guidance about the interaction and impact of inflammation on the selection, use and interpretation of current and new biomarkers specifically and nutrition more broadly. This project was a response to the increasing need expressed by the international nutrition community to address the bidirectional relationship between nutrition and inflammation. It is intended to inform the community on the state of our understanding about these relationships and to identify gaps in knowledge. Objective To summarize results of the INSPIRE deliberations. Results The Scientific Steering Committee and the Secretariat developed four themes as a progression of thought from basic biology to specific nutrition/inflammation relationships and, finally, potential approaches and methodologies to address these relationships. Themes are: (1) Overview of the role of nutrition in immune function/inflammatory response, (2) Specific relationships between nutrients and immune function and inflammatory response, (3) Translating evidence to practice: approaches to addressing the nutrition and inflammation relationships, and (4) Methodologies and new technologies. Working Groups (WG) were constituted and charged with describing the extant evidence on each of the themes and the remaining gaps in knowledge. Conclusion The WGs devised an outline for each theme, work assignments and timeline for drafting a report, which is meant to constitute the main product of this effort. WG members will meet in a workshop in November 28–30, 2012 to hear from invited experts and continue drafting the report. Support: BMGF; NIH.