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Relationship between 25‐hydroxyvitamin D and adiponectin levels in Blacks
Author(s) -
Zarini Gustavo G,
Shaban Lemia,
Exebio Joel C,
McLean Michael,
Huffman Fatma G
Publication year - 2013
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.27.1_supplement.841.4
Subject(s) - adiponectin , medicine , vitamin d and neurology , ethnic group , demography , population , miami , african american , linear regression , gerontology , endocrinology , obesity , insulin resistance , environmental health , mathematics , sociology , ethnology , environmental science , anthropology , soil science , statistics
This study examined the association of 25‐hydroxyvitamin D [25(OH)D] and adiponectin levels in Blacks. This cross‐sectional study included Haitian (n=119) and African Americans (n=199) >; 35 years of age. They were recruited from multiple sources from Miami‐Dade and Broward Counties, Florida, U.S. Twenty ml of venous blood was collected from each participant after an overnight fast. Serum 25(OH)D and adiponectin levels were determined using ELISA methods. Analyses included t‐test, Chi‐square, Pearson's correlations and linear regression. Haitians had significantly lower 25(OH)D (P=.035) and adiponectin levels (P=<.001) as compared to African Americans. Regression analyses showed that after controlling for covariates, the association between 25(OH)D with adiponectin was only significant for African Americans (β=.194, SE= .051, P=.039). The model explained 9.3% of the variability in adiponectin levels. Race/ethnicity is especially disregarded in the Black population living in the U.S. Findings underline the importance of investigating biochemical markers in Black groups as separate and independent ethnicities. Funding for this research was provided through an NIH/NIDDK sponsored grant.