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The Effect of Exercise on the histological analysis in the Shoulder joint of the Aging rat
Author(s) -
Murata Kenji,
Kanemura Naohiko,
Kokubun Takanori,
Fujino Tsutomu,
Takayanagi Kiyomi
Publication year - 2013
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.27.1_supplement.749.3
Subject(s) - enthesis , medicine , tendon , tendinopathy , treadmill , degeneration (medical) , physical therapy , surgery , pathology
Objective Tendinopathy is a common clinical problem at the shoulder joint. Aging leads to the degeneration the supraspinatus tendon, On the other hand, the exercise is vital to the tendon remodeling. In this present study, we observed the effect of periodic exercise using supraspinatus tendon of aged rat. Methods We studied 2‐years‐old male Wister rats were used (n=5), and they were divided into Exercise group (n=4) and Control group (n=1). Exercise group underwent an exercise protocol cosisting of an hour per daily session of treadmill running exercise at a speed of 5.8m/min, 5 days a week for a month. After the experimental periods, sections were cut at 20 μm (frontal plane), and supraspinatus tendon and enthesis were evaluated with histological analysis (Truijin‐blue staining). Result Our results showed that the enthesis degeneration change in the control group compared with the exercise. Furthermore, in the supraspinatus tendon, fiber statue was confirmed in the exercise group, however, in the control group it was difficult to. Conclusion These conditions may suggest that the exercise is one of the remodeling factor for shoulder degeneration, tendenopathy.