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Variants of sacral spina bifida occulta
Author(s) -
Singh Rajani
Publication year - 2013
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.27.1_supplement.746.15
Subject(s) - spina bifida occulta , dorsum , anatomy , spina bifida , medicine , spinal dysraphism , biology , surgery
Precise and systematic knowledge of normal and classified variant anatomy of sacral spina bifida occulta is clinically important for anesthetists, neurologists, radiologists, orthopedic surgeons and academically to anatomists for correlating classes, their genesis and clinical implications. Therefore the study has been carried out. 85 dry sacra were examined, classified in five categories, genetic causes analysed and associated clinical significance was correlated for sacral spina bifida occulta Type‐I the dorsal wall is completely open, Type‐II the dorsal wall is open below S1 down to S5. Type‐III the dorsal wall is open from S2 to S5. Type‐IV the dorsal wall is open below S3 down to S5, Type‐V the dorsal wall is open between S1 and S2. The cause for the genesis of this defect was attributed to the combined effect of mutation of Pax1/Pax9 pair, Hox11 and Foxc genes derived from genetic studies on mice besides environmental factors.