Premium
Temporomandibular joint articular disc: Providing a structural scaffold for use in tissue bioengineering of replacement constructs
Author(s) -
Hove Steven Holterman,
Wilson Tim,
Shimizu Michael,
Merrifield Peter,
Galil Khadry
Publication year - 2013
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.27.1_supplement.744.8
Subject(s) - temporomandibular joint , condyle , scaffold , calipers , joint (building) , orthodontics , cadaver , anatomy , biomedical engineering , medicine , mathematics , engineering , geometry , structural engineering
The temporomandibular joint's (TMJ) articular disc facilitates normal function in the healthy joint. Temporomandibular disorders (TMDs) are associated with disc derangement or damage resulting in joint dysfunction. TMD can progress to an end‐stage where surgical removal of condyle and disc are performed. No adequate prosthetic replacement exists for the disc. A dimensional model for the disc is yet to be provided. Our objective is to assess the dimensions of the articular disc providing a structural scaffold for tissue engineering of replacement constructs. Discs were dissected bilaterally from 12 cadavers (56–100yrs). Linear surface dimensions of the discs were measured using digital calipers to assess absolute and regional anteroposterior width (APW) and mediolateral length (MLL). Regional measurements were taken perpendicularly at relative ratios of the absolute dimensions (50% central; 20% from borders). All measurements (mm) were repeated twice by 2 observers to assess reliability. Mean absolute APW (15.31±1.08) and MLL (24.71±2.29) were calculated from 9 specimens along with mean values for 6 regional surface measurements and 9 regional depth measurements per disc. Within the limits of this study it is possible to provide reliable dimensions for use in creating a structural scaffold of the TMJ articular disc. Grant Funding Source : Departmental Funding