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Functional and morphological changes in the trout heart during thermal acclimation
Author(s) -
Klaiman Jordan M,
Pyle W Glen,
Gillis Todd E
Publication year - 2013
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.27.1_supplement.714.10
Subject(s) - trout , acclimatization , connective tissue , medicine , rainbow trout , ventricle , biology , contractility , diastole , anatomy , endocrinology , fish <actinopterygii> , fishery , ecology , blood pressure , genetics
Rainbow trout remain active in waters that seasonally change between 4ºC and 20ºC. We have previously shown that when male trout are thermally acclimated to the extremes of this temperature range two distinctive cardiac phenotypes emerge. Cardiac hypertrophy is observed in the cold acclimated fish with a concurrent increase in connective tissue and a decrease in the thickness of the compact myocardium, while the opposite occurs in warm acclimated trout. The opposing effects of cold and warm acclimation suggest that male trout can reversibly remodel the morphology and cellular composition of the heart, making the myocardium extremely plastic to changes in environmental temperature. In this study, we use a Langendorff preparation to measure how thermal acclimation and the subsequent cardiac remodeling affects the contractility of the trout heart. With this method we are able to measure maximum systolic and end diastolic pressure. We hypothesized that the increase in connective tissue in cold acclimated males would cause stiffening of the ventricle. Interestingly, preliminary data indicates that the cold acclimated male heart is more compliant then the warm acclimated male heart. This suggests that the remodeling of the myocardial layers has a greater impact on the compliance of the trout heart then connective tissue changes.