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Increases in plasma lutein and zeaxanthin by egg intake is associated with the formation of larger HDL particles in participants with metabolic syndrome
Author(s) -
Blesso Christopher N,
Andersen Catherine J,
Bolling Bradley,
Fernandez Maria Luz
Publication year - 2013
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.27.1_supplement.638.16
Subject(s) - zeaxanthin , lutein , carotenoid , cholesterol , medicine , chemistry , endocrinology , high density lipoprotein , lipoprotein , food science , zoology , biology
We investigated the effects of egg intake on lipoprotein subfractions and size and on plasma lutein and zeaxanthin in metabolic syndrome. Men and women following a carbohydrate restricted diet (25–30% energy) were allocated to consume 3 eggs per day (additional 534 mg of cholesterol, 427 ìg of lutein, 265 ìg of zeaxanthin) (n = 20) or the equivalent amount of egg substitute (additional 0 mg of cholesterol and carotenoids) (n =17) for 12 wk. All subjects increased large LDL (P < 0.05) and decreased small LDL subfractions (P < 0.01). However, increases in the large HDL subfraction were only observed in individuals in the egg group (P < 0.05) Post‐intervention, the egg group had increases in lutein (+ 21%) and zexanthin (+ 43%) while the substitute group had a slight decrease in these plasma carotenoids. Increases in plasma lutein and zeaxanthin were disproportionately due to increases in these carotenoids transported by HDL. We conclude that the higher concentrations of these polar carotenoids in HDL in the egg group may be attributed to a more efficient transport of lutein and zeaxanthin in larger HDL particles [Supported by the American Egg Board]