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Associations between vitamin D status and lipid profiles in military recruits
Author(s) -
McClung James P,
GaffneyStomberg Erin,
Lutz Laura J,
Rood Jennifer C,
Cable Sonya J,
Pasiakos Stefan M,
Young Andrew J
Publication year - 2013
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.27.1_supplement.635.3
Subject(s) - vitamin d and neurology , medicine , population , lipid profile , white (mutation) , military service , endocrinology , demography , physiology , cholesterol , biology , environmental health , history , biochemistry , archaeology , sociology , gene
Recent data suggest a relationship between vitamin D status and cardiometabolic risk factors, especially in populations with cardiovascular disease, although few studies have investigated this association in healthy, young people. This study investigated the relationship between serum vitamin D (25[OH]D) and lipid profiles in military recruits. Blood biomarkers were assessed in fasted volunteers (n = 210, males = 134, females = 76, age [mean ± SD] = 20 ± 3 yrs) within one week of initially reporting for military service. In the total study population, there was a significant positive relationship between serum 25[OH]D and total cholesterol in females (P < 0.05, r = 0.241), but not males (r = 0.067). This relationship was significant in white females (P < 0.05, r = 0.365), but not in non‐white females. There were positive associations between 25[OH]D and HDL in white females (P < 0.05, r = 0.325), but not in males or non‐white females. Similarly, 25[OH]D and LDL levels were associated in white females (P = 0.06, r = 0.256), but not in males or non‐white females. These data suggest sex and race differences in relationships between serum 25[OH]D and lipid profiles in military recruits, with the strongest associations occurring in white females. Future studies should clarify the biological significance of associations between 25[OH]D and lipid profiles in healthy, young populations. Research supported by USAMRMC.