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A pulse‐based diet intervention in women with polycystic ovarian syndrome (PCOS): Compliance, and effects on body composition, fertility and metabolic measures
Author(s) -
Zello Gordon,
Ramachandran Kavitha,
Rooke Julianne J,
Serrao Shani,
Chizen Donna R,
Chilibeck Phil D
Publication year - 2013
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.27.1_supplement.630.5
Subject(s) - lean body mass , medicine , endocrinology , polycystic ovary , obesity , fat mass , body mass index , bone mineral , physiology , zoology , biology , insulin resistance , osteoporosis , body weight
Polycystic ovarian syndrome (PCOS) is an endocrine disorder associated with numerous metabolic complications. We compared body composition (BC) between women with PCOS (n=33) and age‐matched healthy controls (n=16), and also determined the effects of a pulse‐based diet on BC, blood lipids and fertility. Women with PCOS were randomized into groups receiving a pulse‐based diet or the National Cholesterol Education Program therapeutic lifestyle changes (TLC) diet for 16 wk while participating in an aerobic exercise program. Women with PCOS were heavier (+26 kg), had greater fat mass (+23 kg) (both p<0.001), but similar lean tissue mass (LTM) compared to controls. They also had similar bone mineral density, but superior bending strength at the femoral neck (p<0.001) which disappeared after controlling for body mass. After intervention, both diet groups lost a significant amount (p<0.05) of body mass (−4.0 kg), fat mass (−3.1 kg), and trunk fat mass (−1.5 kg) and reduced total cholesterol to HDL ratio (8–10%; p=0.05) with no differences between groups. Both groups maintained LTM mass and bone mineral properties, and number of PC ovaries were reduced. Compliance to meals in the TLC and pulse groups was 79% and 59% respectively. A lower compliance may have been to lack of prior dietary exposure to pulses. A pulse‐based diet is as effective as TLC diet for reducing body fat and improving blood lipids. (Support from Saskatchewan Pulse Growers & Agriculture Agri‐Food Canada)