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Dietary Behavior Modification, With or Without Exercise, Improves Risk Factors for CVD over One Year in Overweight and Obese Lactating Women
Author(s) -
Brekke Hilde Kristin,
Bertz Fredrik,
Rasmussen Kathleen M,
Bosaeus Ingvar,
Ellegård Lars,
Winkvist Anna
Publication year - 2013
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.27.1_supplement.225.5
Subject(s) - overweight , medicine , endocrinology , obesity , weight loss , blood pressure , insulin , cholesterol
Childbearing is associated with increased risk for cardiovascular disease (CVD). Our objective was to examine the effects of Diet (D) and Exercise (E) interventions on cardiovascular fitness, blood lipids, glucose metabolism, cytokines and blood pressure in overweight or obese lactating women using a 2×2 factorial design. At 10–14 wk postpartum, 68 women with a self‐reported prepregnancy BMI of 25–35 kg/m 2 were randomized to a 12‐wk behavior modification treatment with D, E, both or control. The goal of D treatment was to reduce body weight by 0.5 kg/wk through reduced energy intake and of the E treatment was to perform 4 45‐min walks/wk at 60–70% of max heart‐rate. Effects were measured post intervention (12 wk) and 9 mo later (1‐y follow‐up). Two‐way ANCOVA was used to study main and interaction effects adjusted for baseline values. The D treatment produced a 1‐y weight loss of 10%. There was a significant main effect of the D treatment, decreasing fasting insulin ( P <0.05), total cholesterol ( P <0.01) and LDL‐cholesterol ( P <0.01) at the end of the 12‐wk treatment. The decreased insulin was sustained ( P <0.05) and HDL‐cholesterol increased ( P <0.01) at the 1‐y follow‐up. No effects from the E treatment or any interaction effects were observed. Dietary behavior modification produced sustained improvements in risk factors for CVD in overweight and obese lactating women. (Funded in part by the Swedish Research Council.)