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Wound healing effect of TENS in rodents.
Author(s) -
Barreto André Sales,
Souza Siqueira Barreto Rosana,
Souza Siqueira Quintans Jullyana,
Oliveira Donato Isabela,
Cardoso Roberta Santana Deodorio,
Soares Rosilene Calazans,
AlbuquerqueJúnior Ricardo Luiz Cavalcante,
Lucca Waldeci,
Santana Josimari Melo,
QuintansJúnior Lucindo José
Publication year - 2013
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.27.1_supplement.1168.9
Subject(s) - wound healing , medicine , placebo , immunohistochemistry , surgery , pathology , alternative medicine
The aim of this study was to investigate the wound healing activity of low frequency and high frequency TENS on excision wound model in rats. Excision wound: Thirty rats, Wistar , 250–300 g were anesthetized and an excisional wound was performed. The animals was treated with placebo ‐ TENS simulation (equipment off), low‐frequency TENS (2 Hz) and high‐frequency TENS (100 Hz) for 7 days. The residual wounds were analyzed and removed. Experimental protocols were approved by the animal care and use committee at Federal University of Sergipe (CEPA 69/2011). Serial histological sections were obtained and stained by histochemical techniques (Hematoxilin‐Eosin – HE and Sirius red) and immunohistochemical techniques. The results suggest that the high‐frequency TENS reduced (p < 0.05) wound areas. This evidence shows that high‐frequency TENS modulates the wound healing process.