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Pulmonary functions in different phases of menstrual cycle
Author(s) -
Saperova Elena,
Dimitriev Dmitry
Publication year - 2013
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.27.1_supplement.1149.20
Subject(s) - luteal phase , vital capacity , menstrual cycle , follicular phase , medicine , pulmonary function testing , tidal volume , ventilation (architecture) , lung volumes , endocrinology , respiratory system , lung , hormone , lung function , diffusing capacity , mechanical engineering , engineering
The purpose of the present study was to evaluate the influence of the normal menstrual cycle on respiratory parameters. Material and methods Nineteen healthy regularly cycling woman (age 20–25 years) kept daily records of lung function parameters during the follicular phase (FP) and luteal phase (LP) over three menstrual cycles. Results Tidal volume was significantly higher during the LP (0.583±0.017) compared to the FP (0.530±0.015; Mann‐Whitney test (U)=5181.00; p=0.008). Minute ventilation showed the same pattern, being significantly higher during the LP compared with the FP (11.47±0.42 vs 9.82±0.32; U=4801.00; p=0.0007). Peak expiratory flow was significantly higher in LP (6.70±0.08) than in the FP (6.43±0.09; U=5381.50; p=0.026). Breath rate also vas higher during the LP than that during the FP (19.58±0.39 vs 18.42±0.33; U=5342.00; p=0.043). Forced vital capacity, forced expiratory volume in one s, forced expired flow from 25–75% of FVC, forced expired flow at 25%, 50%, 75% of FVC and maximal voluntary ventilation were not different between the cycle phases. In conclusion, lung function changes were found during menstrual cycles in healthy women. Conclusion The luteal increase in lung function parameters suggests a possible role for progesterone or other endogenous sex hormones in stimulating the respiratory drive, either centrally or through the peripheral chemoreceptors or by both.