Premium
A single bout of aerobic exercise prevents the transient endothelial dysfunction induced by mental stress in men with metabolic syndrome
Author(s) -
Sales Allan Robson Kluser,
Fernandes Igor A,
Rocha Natalia G,
Garcia Vinicius P,
Costa Lucas S,
Silva Bruno M,
Nóbrega Antonio C L
Publication year - 2013
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.27.1_supplement.1136.11
Subject(s) - endothelial dysfunction , brachial artery , anaerobic exercise , mental stress , medicine , aerobic exercise , stroop effect , cardiology , metabolic syndrome , endothelium , endocrinology , physical therapy , blood pressure , cognition , obesity , psychiatry
Mental stress induces transient endothelial dysfunction and the association with metabolic syndrome (MetS) may increase the risk for the development of atherosclerosis. Given the beneficial impact of exercise on endothelium function, we hypothesized that a single session of aerobic exercise would prevent the endothelial dysfunction induced by mental stress in men with MetS. Thus, 14 men with MetS (36 ± 4 yrs) initially had their endothelial function assessed through the flow‐mediated dilation (FMD) of the brachial artery (Doppler ultrasound). Subjects were then submitted to a mental stress test (Stroop color), which was followed by either 40 min of leg cycling exercise (80% of the anaerobic threshold) or no exercise in two different sessions. FMD was performed again at 30 and 60 min after exercise (EX) or control (CT), with a mental stress stimulus in between. Mental stress reduced FMD at 30 and 60 min (baseline: 7.7 ± 1.0%; 30 min: 5.0 ± 0.9%; 60min: 3.8 ± 0.8%; p < 0.05) in the CT, whereas EX prevented the endothelial dysfunction caused by mental stress (baseline: 7.4 ± 0.9%; 30 min: 6.2 ± 1.0%; 60 min: 9.3 ± 1.1%; p >; 0.05). In a subgroup (n = 3) where mental stress was not performed, FMD increased at 60 min after the exercise, while no changes were observed in the CT. In conclusion, a single aerobic exercise session prevented the mental stress‐induced endothelial dysfunction in men with MetS. Supported by FAPERJ, FINEP and CNPq.