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Endovascular dual‐sensor composite sensor catheter for the measurement of flow and pressure in rats using telemetry
Author(s) -
Pitsillides Koullis,
Lin Maggie,
Griffiths Leigh,
Uyeminami Dale,
Johnson Katherine,
Pinkerton Kent
Publication year - 2013
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.27.1_supplement.1126.9
Subject(s) - pressure sensor , catheter , blood flow , biomedical engineering , materials science , doppler effect , medicine , surgery , cardiology , engineering , mechanical engineering , physics , astronomy
Measurements of blood flow and blood pressure are typically generated by two separate sensors. We have developed an endovascular catheter that combines a 600‐micron diameter, 20MHz Doppler blood flow sensor and a 330‐micron diameter blood pressure sensor. This dual‐sensor combined sensor catheter is compatible with the EG3‐V1S2T telemetry system (Transonic EndoGear Inc, Davis, CA) that can be used in small animals, such as rats (>;250g). The benefit of such a catheter is that it can be inserted and guided into a blood vessel much like a typical blood pressure only catheter, but with the added advantage of providing both blood flow velocity and blood pressure measurements. The Doppler flow probe has a semispherical lens that allows for a wide angle ultrasound blood vessel illumination, while the blood pressure sensor is a high fidelity solid‐state pressure sensor that is not affected by animal motion, catheter body bending or sensor head elevation changes. Applications for this catheter include the measurement of cardiac output, pulmonary resistance and other parameters. A benefit of abdominal endovascular catheter insertions is that they do not require a thoracic approach, which helps to reduce animal recovery time and mortality.