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NIH/ODS Analytical Methods and Reference Materials (AMRM) Program: Accomplishments and Future Directions
Author(s) -
Betz Joseph M,
Saldanha Leila G,
Cragg Gordon L,
Sorkin Barbara C,
Coates Paul M
Publication year - 2013
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.27.1_supplement.1079.48
Subject(s) - certification , computer science , quality assurance , identification (biology) , certified reference materials , calibration , quality (philosophy) , systems engineering , biochemical engineering , engineering management , engineering , operations management , mathematics , external quality assessment , epistemology , philosophy , botany , statistics , detection limit , political science , law , biology
Assuring the quality of natural products is a challenge to manufacturers, researchers, regulators, and consumers. Because biological materials contain complex mixtures of metabolites, they pose unique analytical challenges. Evaluation of the accuracy, precision and reproducibility of chemical measurements made in these complex matrices is vital. The AMRM Program provides tools to help scientists in the dietary supplement and nutrition communities address these challenges. Program elements include: 1) publicly available methods that have undergone formal validation studies (useful for facilitating method selection and for dispute resolution); 2) suites of certified matrix reference materials for use as method development and method evaluation tools; 3) certified calibration standard solutions for use in analyte identification and instrument calibration; 4) fee‐free laboratory quality assurance programs to assist laboratories in evaluating and improving method, analyst, and laboratory performance. The poster will provide an overview of accomplishments and resources made available by the program, and include future program directions.