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Assessment of folate, vitamin B6 and vitamin B12 status among newly diagnosed Omani cardiac patients
Author(s) -
Waly Mostafa I.,
Ali Amanat,
AlFarsi Yahya M.,
Ouhtit Allal,
AlNassri Amira,
Arafa Mostafa
Publication year - 2013
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.27.1_supplement.1078.4
Subject(s) - hyperhomocysteinemia , medicine , vitamin b12 , homocysteine , vitamin b6 , physiology , vitamin , etiology , pyridoxine , gastroenterology
Background Oman is currently witnessing an increase in the rate of morbidity and mortality from non‐communicable diseases, including cardiovascular diseases (CVD). Objectives This study was aimed to assess the nutritional and biochemical status of folate, vitamin B6 and vitamin B12 in relation to homocysteine level in newly diagnosed Omani cardiac patients. Methods and Subjects A case‐control study included 25 cases, recently diagnosed Omani cardiac patients, and 25 age and gender matched healthy subjects as a control group. Results As compared to control group, the enrolled Omani cardiac patients had lower dietary intake of folate, vitamin B6 and vitamin B12 that is concomitant with low serum levels of these three nutrients, P<0.05. The patents had hyperhomocysteinemia that was negatively correlated with the status of folate, vitamin B6 and vitamin B12, and they consumed high protein and saturated fats from animal sources in amount that exceeds the recommended daily dietary intake. Conclusion Hyperhomocysteinemia and low status of folate, vitamin B6 and vitamin B12 are involved in the aetiology of CVD among high risk groups.