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A randomized, crossover comparison of the effects of high fructose corn syrup versus sucrose intake on basic physiologic measures
Author(s) -
Mouch Erica M,
Walz Alyssa M,
Tomaj Leonita,
Carbone John W
Publication year - 2013
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.27.1_supplement.1074.7
Subject(s) - high fructose corn syrup , crossover study , ingestion , sucrose , fructose , corn syrup , food science , heart rate , chemistry , caffeine , zoology , endocrinology , blood pressure , medicine , biology , placebo , alternative medicine , pathology
High fructose corn syrup (HFCS) has received growing attention and controversy in both popular and scientific media for its potential to differentially influence risk factors associated with metabolic syndrome, relative to sucrose (SUC). To date, no studies have examined the effects of acute ingestion of HFCS versus SUC on basic physiologic measures. The current study compared the effects of acute HFCS and SUC intake on blood pressure (BP), heart rate (HR), body temperature (BT) and blood glucose (BG) levels. Thirteen healthy, fasted men (n=3) and women (n=10) participated in a crossover design study, consuming caffeine‐free carbonated beverages (355mL) sweetened with either HFCS (37g) or SUC (37g) on separate days. BP, BT, HR, and BG were measured at baseline and 5min, 30min and 120min post‐consumption. A sweetener‐by‐time interaction (P = 0.02) was observed for HR, with mean 30min measures higher for HFCS (72 ± 3bpm) relative to SUC (65 ± 3bpm). Regardless of sweetener, BG was higher at 5min and 30min compared to baseline and 120min (P < 0.001); BT was lower at 5min compared to all other timepoints (P < 0.001). These data suggest the potential for a differential influence of sweetener type on HR and illustrate the effect of nutritive sweetener ingestion on BG and BT. Further study is warranted to establish the mechanistic basis for the observed effects. Supported by EMU URSP