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Adiponectin levels in individuals with type 2 diabetes on a high fiber or a low glycemic index diet.
Author(s) -
Augustin Livia SA,
Mejia Sonia Blanco,
Mirrahimi Arash,
Mitchell Sandra,
Connelly Philip,
Kendall Cyril WC,
Jenkins David JA
Publication year - 2013
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.27.1_supplement.1067.14
Subject(s) - adiponectin , medicine , glycemic , type 2 diabetes , endocrinology , glycemic index , diabetes mellitus , insulin resistance
Objectives Adiponectin is considered to have anti‐diabetic, antiinflammatory and anti‐atherogenic effects. We investigated whether adiponectin levels correlated with cardiovascular risk factors in a cohort of people with type 2 diabetes and whether improving glycemic control through diet may increase adiponectin levels. Research Design and Methods Post‐hoc analysis of 156 men and women with type 2 diabetes who participated in a dietary study of low glycemic index (LGI) or a high cereal fiber diet (HCF) for 6 months with the aim of improving blood glucose control. Results Significant (p<0.05) negative correlations were seen at baseline with triglycerides (TG) in men and women and positive correlations with HDL‐cholesterol (HDL‐C) in women and with LDL‐C and total cholesterol in men. Adiponectin levels increased similarly in both diets: 9 percent (%) from baseline in the HCF diet and 14% in the LGI diet (p<0.01). A significant (p<0.01) negative correlation was observed between % baseline changes in adiponectin and HbA1c in women, after adjustment for body weight changes. Conclusions Improving glycemic control through diet may improve adiponectin levels in people with type 2 diabetes. Study supported by Barilla