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Sociodemographic, clinical, and lifestyle factors associated with prostate cancer aggressiveness in a population‐based study
Author(s) -
Vance Terrence M,
Wang Ying,
Su L. Joseph,
Fontham Elizabeth T. H.,
Bensen Jeannette T.,
Mohler James L.,
Chen MingHui,
Chun Ock K.
Publication year - 2013
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.27.1_supplement.1061.2
Subject(s) - medicine , prostate cancer , marital status , demography , gerontology , population , epidemiology , cancer , environmental health , sociology
This study aimed to determine the associations between sociodemographic, clinical, and lifestyle factors and prostate cancer (PCa) aggressiveness. Data are from the North Carolina‐ Louisiana Prostate Cancer Project, a population‐based study of incident PCa in African Americans (AA) (n=925) and Caucasian Americans (CA) (n=1,059). Medical record abstraction and structured questionnaires were used to collect data. PCa patients with higher aggressiveness were greater among AA than CA. Aggressive cases were greater among men older at diagnosis, not married, less educated, with lower income, without previous screenings or health insurance, and with greater BMI and waist‐hip ratio (WHR) than their counter parts (p<0.05). When stratified by race, several factors were found to differ between AA and CA, including age, marital status, education, poverty, health insurance status, PSA screening, and supplement use (p<0.05). These results suggest that differences in several sociodemographic, clinical, and lifestyle factors may contribute to the disparity in PCa aggressiveness observed between AA and CA. Grant Funding Source : NIH Cancer Epidemiology Small Grant #1R03CA159421–01A1.