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Fructose, sweetened food and beverage intake and metabolic markers in children
Author(s) -
County Christine,
Thomas Alicia,
Catalano Patrick M.,
Nock Nora L.
Publication year - 2013
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.27.1_supplement.1060.18
Subject(s) - fructose , high fructose corn syrup , leptin , endocrinology , medicine , insulin resistance , metabolic syndrome , obesity , hyperuricemia , added sugar , dyslipidemia , corn syrup , insulin , food science , uric acid , chemistry
Over the past three decades, high fructose corn syrup (HFCS) has replaced about one‐third of the sugar consumption in the U.S. and, interestingly, this increase parallels the rise in obesity. In contrast to glucose, fructose is not regulated by insulin or cellular energy status; and, in animals, fructose administration increases hyperuricemia, dyslipidemia, blood pressure, glucose intolerance and leptin resistance. However, the role of fructose on metabolic dysfunction in children has not been well explored and additional studies are needed to better inform policy. Thus, we examined associations between fructose and metabolic markers (fasting glucose, insulin, TG, HDL, LDL, leptin, TNF‐á, BP, weight, BMI) in 89 children, 6–11 years old, born from women with and without gestational diabetes mellitus (MGD). Previous results from this cohort have shown that children in the highest tertile of the CDC percentiles had significantly greater carbohydrate intake and fasting insulin and leptin levels. Analyses evaluating the intake of fructose, HFCS and sweetened foods and beverages on metabolic markers are underway and will be presented for the total sample and stratified by the presence or absence of MGD. Grant Funding Source : NIH NCI K07129162