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The effect of more vegetable intake on risk factors for cardiovascular disease in hemodialysis patients
Author(s) -
Wu PeiYu,
Chiu YiFang,
Lu YuJu,
Chen HsiHsien,
Su ChienTien,
Yang ShwuHuey
Publication year - 2013
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.27.1_supplement.1057.14
Subject(s) - medicine , homocysteine , triglyceride , insulin resistance , body mass index , c reactive protein , hemodialysis , lipid profile , cholesterol , gastroenterology , endocrinology , insulin , inflammation
Objective To evaluate the effect of more vegetable intake on cardiovascular disease risk factors in hemodialysis (HD) patients. Methods This is a cross‐sectional study. All subjects were outpatients from Taipei Medical University Hospital. Fifty‐four HD patients and thirty‐five subjects with eGFR more than 60 ml/min/1.73m 2 from department of Family Medicine (control group) were completed this study. The dietary components and nutrients intake was calculated from the average of 3‐day dietary record. Besides, the nutritional markers (dry body weight and serum albumin), inflammatory markers (serum C‐reactive protein), lipid profile (serum total cholesterol, low‐density lipoprotein cholesterol, and triglyceride), serum folate, homocysteine, and potassium, and insulin resistance index were analyzed by Department of Laboratory Medicine of Taipei Medical University Hospital. Both HD patients and control group were dichotomy by median of vegetable intake adjusted by energy, and the cut point in HD patients was 1.05 servings of vegetable/1000 kcal. Results Comparing with control group, HD patients had significantly higher serum level of C‐reactive protein and homocysteine, and insulin resistance index, but lower serum albumin level. Despite the vegetable intake was not significantly different between HD patients and control group, even after adjusting for energy intake. HD patients with higher vegetable intake had lower serum C‐reactive protein and homocysteine, and insulin resistance index, but did not achieve statistical significance. Conclusion In HD patients, more vegetable intake may not be associated with improving selected risk factors for cardiovascular disease in this study.