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The components of metabolic syndrome in relation to weight status in South Indians
Author(s) -
Must Aviva,
Thanikachalam Mohan,
Begum Mubeen,
Vijayakumar Harivanza,
Chui Ken,
Chomitz Virginia,
Bermudez Odilia,
Thanikachalam Sadagopan
Publication year - 2013
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.27.1_supplement.1055.15
Subject(s) - underweight , medicine , waist , obesity , metabolic syndrome , anthropometry , body mass index , demography , population , diabetes mellitus , blood pressure , national cholesterol education program , endocrinology , overweight , environmental health , sociology
Asian populations have elevated risk for obesity‐related morbidity such as metabolic syndrome (MS). MS, defined as the presence of 3 of 5 cardiovascular and anthropometric indicators, may overlook differences in its components relative to modifiable antecedents, such as weight. A population‐based cross‐sectional survey in 8042 (44% M, 56% F) South Indians collected detailed physicals and biochemical assays via standard protocols. MS components were defined based on the modified National Cholesterol Education Program Adult Treatment Panel (ATPIII) criteria for Asians. BMI categories were <18.5, 18.5–23, 23–25, 25–30, and 30+. 11% M and 7% F were underweight (BMI<18.5); prevalence of BMI>;23 was 56% M and 70% F; with 6% M and 16% F with BMI >;30. MS components were prevalent across all weight groups BMI >;18.5, with ranges 27 to 59% M and 18 to 80% F. Compared to normal weight (BMI 18.5–23), after adjusting for smoking (males only) and age, prevalence ratios (PRs) for triglycerides, high density lipoproteins, elevated blood pressure/hypertension, and fasting plasma glucose/diabetes showed patterns of increasing risk across BMI categories, with PRs of 1.3 to 1.7 M and 1.2 to 2.1 F in the BMI 30+ category. Results were similar for waist circumference categories. Overall, the risk gradient is less apparent than observed in western populations, likely due to the high prevalence of these risk factors in normal weight groups.