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Associations between nutritional status of micronutrients and the growth, body composition and biomarkers of metabolic risk in Chilean children
Author(s) -
Romana Daniel Lopez,
Corvalan Camila,
Uauy Ricardo,
Cediel Gustavo,
Duran Gabriela,
Palomino Ana Maria
Publication year - 2013
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.27.1_supplement.1055.11
Subject(s) - micronutrient , medicine , endocrinology , obesity , hepcidin , overweight , anthropometry , soluble transferrin receptor , adiponectin , vitamin d and neurology , leptin , insulin , iron deficiency , insulin resistance , anemia , iron status , pathology
The associations between micronutrients and obesity and/or chronic diseases are not consistent. Methods Cross‐sectional study of 300, 8–11 y children. The following measurements were obtained: 1) Anthropometry: weight (wt), height (ht), zBMI; 2) Body composition: % body fat; 3) Biomarkers metabolic risk: insulin, glucose, serum lipids, adiponectin, leptin; 4) Micronutrient indicators: hemoglobin (hb), serum ferritin (SF), serum transferrin receptors (TfR), hepcidin, plasma zinc (ZnPl) and serum VD concentrations (25OHD). Results 26% of children were overweight and 29% obese. None of the children were anemic or Zn deficient. 4% were Fe deficient and 28% VD deficient. No associations were found between FS or 25OHD and either wt, ht, % fat or metabolic risk indicators. A significant direct association was observed between TfR and Wt (r 0.24), ht (r 0.14), zBMI (r 0.25), % body fat (r 0.22). Significant correlations were found between hepcidin and both wt (r −0.12) and zBMI (r −0.12). ZnPl correlated with % body fat (r 0.12) and insulin (r −0.20). No significant differences in Hb, SF, hepcidin or 25OHD were found between obese (Ob) and non‐obese children. Both TfR and ZnPl were significantly higher in Ob children. Conclusions Vitamin D status is not associated to Ht, % body fat or biomarkers of metabolic risk. Ob children had higher ZnPl and TfR concentrations than N children. Source of funding: FONDECYT research grants 1090252, 1100206 and 1110085.