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Insufficient folate intake increased arterial stiffness in former smokers with type 2 diabetes
Author(s) -
Kim Yeonsoo,
Choi Young Ju,
Huh Kap Bum,
Chang Namsoo
Publication year - 2012
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.26.1_supplement.lb403
Subject(s) - arterial stiffness , pulse wave velocity , medicine , type 2 diabetes , diabetes mellitus , anthropometry , cardiology , endocrinology , physiology , blood pressure
The objective of the present study was to investigate the interaction between smoking cessation and nutrient intake on arterial stiffness in patients with type 2 diabetes. A cross‐sectional study was conducted with 322 patients with type 2 diabetes (216 never smokers and 106 former smokers). Anthropometric, biochemical, dietary data and brachial‐ankle pulse wave velocity (baPWV) were collected. BaPWV was higher in type 2 diabetic, former smokers who consumed sufficient dietary folate that those who consumed insufficient dietary folate although baPWV was not significaly different in never smokers based on sufficient intake of folate. Moreover, in correlation analyses adjusted for age, sex, and BMI, there was borderline significant correlation between vegetable, a major food source of folate, and baPWV in former smokers with type 2 diabetes. The results of the current study showed that insufficient folate intake, which is lower than the estimated average requirement, increased arterial stiffness in former smokers with type 2 diabetes. The results of the current study warrant future studies to explore any mechanisms involved in beneficial effects of dietary folate intake on arterial vessel stiffness in former smokers with type 2 diabetes.