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Effects of Capsicum L. var. annuum and Capsicum annuum L. Species Water Extracts on Lipid Metabolism‐Related Enzymes Activities in 3T3‐L1 Cell
Author(s) -
Kim Kyoungkon,
Lee Jaesung,
Heo Jeongwon,
Baek Jongmi,
Kim Taehyuk,
Kim Daejung,
Kim Taewoo,
Kim Cheonan,
Choe Myeon
Publication year - 2012
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.26.1_supplement.lb146
Subject(s) - capsicum annuum , enzyme , lipid metabolism , lipoprotein lipase , hormone sensitive lipase , metabolism , lipase , biology , biochemistry , chemistry , horticulture , pepper
Obesity was long been known as a negative factor for improving average life span. Therefore, a therapeutic approach using natural compounds has been proposed as a novel strategy for preventing metabolic disorders. In the present study, we investigated the anti‐obesity effect of Capsicum L. var. annuum and Capsicum annuum L. species water extract supplemented to 3T3‐L1 cells. The gene expression of lipid metabolism‐related enzymes, such as lipoprotein lipase (LPL), hormone sensitive lipase (HSL), acyl CoA synthetase(ACS) and carnitine palmitoyltransferase‐1(CPT‐1), were measured by reverse transcription polymerase chain reaction (RT‐PCR).