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Morphological Changes of the Membranous Labyrinth in Meniereˈs Disease
Author(s) -
Tanioka Hisaya,
Kaga Kimitaka
Publication year - 2012
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.26.1_supplement.904.4
Subject(s) - meniere's disease , membranous labyrinth , utricle , saccule , medicine , endolymphatic hydrops , vestibular aqueduct , volume rendering , vestibular system , high resolution , radiology , rendering (computer graphics) , disease , pathology , computer science , artificial intelligence , geology , remote sensing
Objectives To image morphological changes of the membranous labyrinth in Meniere's disease using direct volume rendering by temporal bone high‐resolution CT exam. 3D reconstructed images of endolymphatic hydrops with direct volume rendering generate morphological changes in Meniere's disease. Study Design In vivo retrospective clinical study during pre‐attack, attack and recovery periods in Meniere's disease. Patients Patients with Meniere's disease who were examined at three stages, namely, pre‐attack, attack and recovery period. Methods All CT images were acquired on a row CT scanner. The axial data were applied to create 3D volume rendering images on the CT work station for post processing with the factory preset soft ware. Results 3D images of the membranous labyrinth in Meniere's disease demonstrate different morphologic change in proportion to periods. On attack period, the saccule and utricle was enlargement in comparison with pre‐attack period and recovery period. Patients were treated by increases in vestibular, systematic blood flow and decreases in blood pressure. Conclusion We reported the first visualization of endlymphatic hydrops in patients with Meniere's disease that were consistent with periods.