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Soybean or Fish Oil Increases Adiponectin and Nitric Oxide Levels and Decreases Blood Pressure in Metabolic Syndrome
Author(s) -
Dichi Isaias,
Simão Andréa Name Colado,
Lovozoy Marcell AB,
Morimoto Helena Kaminami,
Simão Tathiame Colado,
Dichi Jane Bandeira
Publication year - 2012
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.26.1_supplement.819.28
Subject(s) - fish oil , adiponectin , blood pressure , medicine , nitric oxide , metabolic syndrome , endocrinology , zoology , fish <actinopterygii> , biology , insulin resistance , obesity , fishery
Sixty five women (mean age 47,9 ± 9,98 y) were studied in a 90 days parallel randomized design. A control group maintained their usual diet; the second group received 29 g/day of soy bean (kinako); the third group received 3 g/day of fish oil n‐3 fatty acids; and the fourth group received fish oil (3 g/day) and kinako (29 g/day). Anthropometric, blood pressure, inflammatory markers, anti‐inflammatory marker (adiponectin) and nitric oxide (NO) concentrations were evaluated. In relation to the baseline values, the group that received fish oil and kinako concomitantly presented statistically significant decrease in systolic blood pressure (p<0,05), whereas there was a significant decrease in diastolic blood pressure (DBP) in the control group (p<0,05), kinako group (p<0,01), and fish oil group (p<0,01) after 90 days, There was a significant increase in adiponectin (p<0,01) and NO values (p<0,05) after 90 days in the kinako and fish oil groups. Differences between treatment groups verified a significant decrease (p<0.05) in DBP in kinako group after 90 days when compared to the results obtained from fish oil and kinako group. In conclusion, the findings of increased serum adiponectin and NO metabolite levels after 90 days both in fish oil and soy groups reinforce the importance of the influence of adiponectin and NO levels on blood pressure decrease in patients with MetS.