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BOLD (Beef in an Optimal Lean Diet) effects on metabolic syndrome: a preliminary analysis
Author(s) -
Hill Alison Marie,
Roussell Michael,
West Sheila,
Kris-Etherton Penny
Publication year - 2012
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.26.1_supplement.819.24
Subject(s) - weight loss , beef cattle , dash , zoology , medicine , food science , endocrinology , chemistry , obesity , biology , computer science , operating system
Primary treatment for Metabolic Syndrome (MS) is weight loss; yet dietary weight loss interventions emphasizing different types and amounts of PRO may elicit different effects on the MS risk profile. Volunteers (n=62) with MS (ATP III criteria) completed a 25‐week randomized parallel dietary intervention involving three phases: controlled weight maintenance, controlled weight loss and free living weight loss. All subjects were fed an Average American Diet (AAD) [13% saturated fatty acids (SFA), 17% protein (PRO), ~1.4 oz beef/d] for 2 weeks (baseline) before consuming one of three cholesterol‐lowering diets: Modified‐DASH [ <7% SFA, 18% PRO (2/3 plant sources), ~0.4 oz beef/d], BOLD [<7% SFA, 19% PRO (2/3 animal sources), ~5.0 oz beef/d], and BOLD+ ( <7% SFA, 27% PRO, ~7.0 oz beef/d). Criteria for MS were assessed at baseline, at the end of the controlled feeding periods and after free living. Significant equivalent improvements in MS criteria were observed for all experimental diets compared with baseline (P<0.05); the greatest benefit was seen in the controlled weight loss phase, with regression toward baseline during free living. These data suggest that heart‐healthy dietary patterns that emphasize animal or plant protein can improve criteria for MS when SFA is controlled. Supported by: National Cattlemen's Beef Association.