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Obesity and serum high sensitivity C‐reactive protein in Turkish immigrants with type 2 diabetes
Author(s) -
Sukram Shiryn D.,
Zarini Gustavo G.,
Huffman Fatma G.
Publication year - 2012
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.26.1_supplement.817.2
Subject(s) - medicine , confounding , obesity , type 2 diabetes , anthropometry , turkish population , population , c reactive protein , demography , linear regression , turkish , body mass index , glycemic , diabetes mellitus , endocrinology , gastroenterology , biology , mathematics , environmental health , statistics , genetics , linguistics , philosophy , sociology , genotype , inflammation , gene
The study examined the associations of anthropometric indices of obesity with high sensitivity C‐reactive protein (hs‐CRP) in Turkish immigrants with T2D. A total of 110 subjects, physician‐diagnosed with T2D, aged 30 years and older were recruited from multiple sources from The Hague, Netherlands. Subjects with hs‐CRP levels >10 mg/L (n=17) were excluded from the analysis. Serum hs‐CRP were measured with immuno‐turbidimetric assay. Glycemic control (A1C) was determined by high‐pressure liquid chromatography. Analysis included descriptive statistics, Pearson's correlations and multiple linear regressions stratified by gender. Hs‐CRP was log transformed to achieve normality. Females had a higher BMI (P=0.007) and WHtR (P=0.011) as compared to males. Conversely, males had a higher WHpR (P<0.001) than females. Multiple linear regressions showed that after controlling for confounding variables log hs‐CRP was positively associated with WHtR (β=4.015, P<0.01), WC (β=0.025, P<0.05), and BMI (β=0.039, P<0.05) in females only. Our findings of gender specific obesity indices in relation with hs‐CRP need to be further investigated in the Turkish immigrant population. Hs‐CRP assessment may be added as a standard of care for T2D treatment within this population.