Premium
Anthropometry in achondroplasia adults
Author(s) -
Henry Bobbie,
Koerner Celide,
Alade Yewande,
Schulze Kerry,
Hoover-Fong Julie
Publication year - 2012
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.26.1_supplement.809.4
Subject(s) - achondroplasia , medicine , anthropometry , macrocephaly , waist , population , physical therapy , pediatrics , body mass index , environmental health
Background Achondroplasia is the most common short stature skeletal dysplasia with macrocephaly, lordosis, and rhizomelia. Elevated hypertension prevalence and earlier median cardiovascular disease death are prompting research to elucidate the cause in this population. Standardized anthropometry methodology, for correlation with health outcomes, is needed for accurate assessment of body measurements in achondroplasia. Methods 20 adults with achondroplasia (11 M,9 F) had extensive anthropometric evaluation. Results Aberrant skinfolds, displaced anatomic landmarks, and excessive body fat necessitated modification of most measures and dismissal of triceps and subscapular skinfolds and iliac crest waist circumference. Reliable measurements requiring minimal or no modifications included maximal hip, umbilical and neck circumference, height and weight. Stratified by gender, only hip circumference (male 91.9±10.9 cm, female 109.6±9.3 cm) was statistically significantly different (p = 0.001). Discussion These measures were readily accessible without specialized equipment. Novel standardized methodology are now established for the clinical setting and future health outcomes research in achondroplasia. Research support from the Alan and Kathryn Greenberg Center for Skeletal Dysplasias, McKusick‐Nathans Institute of Genetic Medicine, Johns Hopkins University