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Early Anatomical Identification Markers for Duchenne Muscular Dystrophy in a Subadult Subject
Author(s) -
Harris Jasmine H.,
Godwin Ellen,
Marquez Samuel
Publication year - 2012
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.26.1_supplement.723.10
Subject(s) - physical medicine and rehabilitation , gait , duchenne muscular dystrophy , gait analysis , medicine , pelvic tilt , kinematics , motion capture , range of motion , motion analysis , physical therapy , motion (physics) , pelvis , anatomy , computer science , artificial intelligence , physics , classical mechanics
Duchenne Muscular Dystrophy (DMD) readily affects gait and posture in subadult populations afflicted with the disease. This study used instrumented motion analysis (IMA) to identify how gait and posture changes respond to DMD disease. 3‐D motion analysis was performed with the Vicon Motion Capture System on a 5‐year‐old boy suspected with DMD. Thirty‐nine reflective markers were placed on specific anatomical landmarks according to the Plug‐in‐Gait Model used with the Vicon system. The child walked across the 25 feet gait analysis laboratory for 10 trials. A single representative trial was selected for analysis. Kinematic parameters of gait were compared to those of a typically developing child. IMA identified specific changes in joint kinematics in the child with DMD as compared to the typically developing child. Changes include: increase in anterior pelvic tilt and hip flexion in swing, genu recurvatum in stance, plantar flexion on initial contact with ground, and lack of dorsiflexion in swing. These gait deviations are commonly found in boys with DMD. The results show the ability to identify these changes translating in the early diagnosis of DMD as they represent a specific pattern of walking that is related to the progression of weakness observed. Identification of anatomical gait deviations can assist in the development of treatment interventions to assist the child to be ambulant as long as possible. Grant Funding Source : None