Premium
Salty taste acuity in relation to zinc nutritional status and αENaC A663T gene polymorphism among Korean young adults
Author(s) -
Noh Hwa Young,
Paik Hee Young,
Chung Jayong
Publication year - 2012
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.26.1_supplement.647.8
Subject(s) - epithelial sodium channel , taste , genotype , medicine , sodium , food science , biology , gene , chemistry , genetics , organic chemistry
Taste perception for salt affects the dietary salt intake, of which in excess is a major public health concern. Zn status and genetic factors have been associated with altered taste perception. In this study, we examined the association between zinc status, α‐epithelial sodium channel (αENaC) A663T genotype and salty taste acuity in 207 free‐living healthy young adults (20–29yr). Salty taste acuity were determined by sensory test. Dietary Zn intake data was collected by one 24‐h recall and two‐day dietary record. Serum Zn was measured by atomic absorption spectrometry. αENaC genotype was identified by the PCR‐restriction fragment length polymorphism method. We found that available Zn intake had positive association with the salty taste acuity only in female ( P =0.02). Serum Zn had no effect on salty taste perception in both gender groups. When subjects were stratified according to αENaC genotype, only in females with AA genotype, available Zn intake had negative association with salty taste threshold (β= 0.833, P =0.02). In conclusion, our data shows that Zn intake affects the salty taste acuity in young females. Further, the effect of Zn intake on salty taste acuity is differed by αENaC genotypes, suggesting dietary guideline to reduce Na intake may depends on αENaC genotypes and gender of target group. This study was supported by National Research Foundation (KFR‐2008‐313‐C00978).