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Egg Consumption and Coronary Heart Disease among Diabetic Individuals: A Systematic Review of the Literature
Author(s) -
Tran Nga L.,
Barraj Leila M,
Heilman Jacqueline
Publication year - 2012
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.26.1_supplement.633.8
Subject(s) - confounding , medicine , type 2 diabetes mellitus , diabetes mellitus , epidemiology , disease , type 2 diabetes , metabolic syndrome , coronary heart disease , meta analysis , prospective cohort study , environmental health , physiology , endocrinology
This study reviews epidemiological and experimental evidence on the relationship between egg consumption and coronary heart disease (CHD) risks among type II diabetes mellitus (T2DM) individuals and T2DM risk in non‐diabetic subjects. Four of the six studies that examined cardiovascular disease and mortality and egg consumption among diabetics found a statistically significant association. Of the seven studies evaluating incident T2DM and egg consumption, three prospective studies found a statistically significant association. Lack of adjustment for dietary confounders was a common study limitation. Differences in study design, T2DM status, exposure measurement, subject age, control for confounders and follow‐up time limit the feasibility of a meta‐analysis. A small number of experimental studies examined the relationship between egg intake and CHD risk biomarkers among diabetics or individuals with T2DM risk factors. Conflicting results coupled with small sample sizes prevent broad interpretation. Studies among healthy subjects found suggestive evidence that dietary interventions including eggs may reduce the risk of T2DM and metabolic syndrome. Given the study limitations, these findings need to be further investigated.