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Association between vitamin D status, cardiometabolic risk factors and metabolic syndrome in Puerto Rican adults
Author(s) -
Palacios Cristina,
Perez Cynthia,
Guzman Manuel,
Ortiz Ana Patricia,
Suarez Erick
Publication year - 2012
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.26.1_supplement.386.5
Subject(s) - metabolic syndrome , medicine , vitamin d and neurology , odds ratio , endocrinology , obesity
Objective Vitamin D status has been related to several risk factors in Whites. This pilot study assessed the association between vitamin D status and cardiometabolic risk factors in Hispanics from Puerto Rico. Methods Secondary analysis of a household survey with a representative sample of 859 adults of San Juan. Serum 25(OH)D levels were measured with HPLC‐MS and categorized as <30 or ≥30 ng/ml. Age‐adjusted partial correlations were calculated between serum 25(OH)D and blood pressure, HDL‐C, non HDL‐C, LDL‐C, triglycerides, fasting blood glucose, glycosylated hemoglobin, hs‐C reactive protein, fibrinogen and plasminogen. The association between categories of serum 25(OH)D and risk factors was assessed using test‐based methods. Results Preliminary results in 91 adults (53 females; 38 males) showed that mean serum 25(OH)D was 36.3±7.5 ng/mL, and it was significantly lower in females (34.8 vs 38.3 ng/mL; p=0.01). Only 17.6% had levels below 30 ng/ml. Serum 25(OH)D was significantly correlated with HDL‐C (r=0.28; p=0.03) and number of metabolic syndrome components in females (r=−0.30; p<0.05) and WHR in men (r=−0.35; p=0.04). Only females with levels <30 ng/ml had higher odds of metabolic syndrome compared to those with levels ≥30 ng/ml (OR=4.93, p=0.03). Conclusions These findings suggest that low serum 25(OH)D is associated with increased odds of metabolic syndrome in females.