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A randomized trial of genetic information for personalized nutrition on behaviour outcomes
Author(s) -
Nielsen Daiva E,
El-Sohemy Ahmed
Publication year - 2012
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.26.1_supplement.380.8
Subject(s) - randomized controlled trial , intervention (counseling) , feeling , advice (programming) , genetic testing , test (biology) , medicine , psychology , family medicine , social psychology , psychiatry , biology , paleontology , computer science , programming language
Personal genetic information has become increasingly accessible to the public as a result of direct‐to‐consumer genetic tests, however, concerns have been raised over their value and potential risks. We compared the effects of providing genotype‐based dietary advice with general recommendations on behaviour outcomes using a randomized controlled study. Subjects aged 20–35 years (n=138) were randomized to an intervention (I) or control (C) group and were given a report of either genotype‐based or general dietary advice, respectively. A survey was completed to assess understanding and opinions of the reports. Responses were given on a 5‐point scale ranging from “strongly agree” to “strongly disagree”. Subjects reporting “strongly agree” or “somewhat agree” were grouped and the chi‐square test was used to compare frequency of “agree” to all other responses. Subjects in the intervention group were more likely to agree that they understood the report (93% (I) vs. 78% (C); p=0.009), that the advice would be useful when considering diet (88% (I) vs. 72% (C); p=0.02) and that they would like to know more about the dietary advice (95% (I) vs. 76% (C); p=0.001). Only 9% of subjects in the intervention group reported feeling uneasy about learning their genetic information. These findings suggest that individuals find dietary recommendations based on genetics more understandable and more useful than general dietary advice. Grant Funding Source : Advanced Foods and Materials Network