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Concomitant use of dietary supplements and prescription medications among U.S. adult civilians with a doctor‐informed chronic disease: NHANES 2005–2008
Author(s) -
Farina Emily Kristin,
Austin Krista G,
Fulgoni Victor L,
Lieberman Harris R
Publication year - 2012
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.26.1_supplement.379.2
Subject(s) - medicine , multivitamin , national health and nutrition examination survey , concomitant , medical prescription , diabetes mellitus , disease , vitamin d and neurology , kidney disease , vitamin , population , environmental health , endocrinology , pharmacology
Potential interactions between dietary supplements (DS) and prescription medications (PM) is of concern for both military and civilian populations, yet prevalence of concomitant DS and PM use is not well documented. Thus, we determined prevalence and likelihood of DS and PM use as a function of a doctor‐informed, chronic disease (vascular, arthritis, respiratory, liver, renal, thyroid, cancer, osteoporosis, or diabetes) among U.S. civilian adults (n=9,027; mean age=47 y), using National Health and Nutrition Survey (NHANES), 2005–2008 data. Subjects with a chronic disease were more likely to use DS (OR, 95% CI=1.44, 1.24–1.68), PM (OR, 95% CI=4.17, 3.60–4.83), and concomitantly use DS and PM (OR, 95% CI=3.01, 2.56–3.52) than those without a chronic disease, after adjustment for age, gender, marital status, education, and income. The most prevalent DS used with a PM was a standard multivitamin and mineral (MVM) among those with, and without a chronic disease. However, this prevalence was higher among those with a chronic disease (18.2%±0.5 compared to 7.3%±0.6; P <0.01). Prevalence of individual non‐MVM subgroups and PM was low in both groups (< 2.0%), but combined use of all non‐MVM subgroups with a PM was higher in those with a chronic disease (7.7%±0.5 compared to 2.5%±0.4; P <0.1). These findings demonstrate that presence of a chronic disease may be an important predictor of DS and PM use.