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Lower dairy calcium and dairy vitamin D intakes are associated with increased skeletal muscle fatty infiltration in adolescent girls
Author(s) -
Vassallo Danielle,
Lee Vinson,
Laudermilk Monica,
Blew Rob,
Going Scott
Publication year - 2012
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.26.1_supplement.369.2
Subject(s) - medicine , vitamin d and neurology , endocrinology , calcium , quantitative computed tomography , zoology , bone mineral , osteoporosis , biology
BACKGROUND Fat infiltration within skeletal muscle is strongly associated with type 2 diabetes mellitus. Insufficient calcium (Ca) and vitamin D (VitD) intake is common in youth and has been associated with the development of obesity and osteoporosis. Dairy Ca and VitD are better absorbed compared to other dietary sources and have been linked to decreased adiposity. OBJECTIVE Examine the relationships between dairy Ca and VitD with skeletal muscle fat infiltration (SMFI) in 212 healthy girls aged 8–13 years. METHODS Muscle density (mg/cm 3 ), an index of fat infiltration, was measured at the 66% tibia and 20% femur sites (relative to distal growth plates) on the non‐dominant limb using peripheral quantitative computed tomography (pQCT). Dairy Ca and VitD were assessed using the Harvard youth adolescent questionnaire (YAQ). RESULTS Multiple linear regressions with dairy Ca and VitD, maturity, total caloric intake, and activity (pedometer steps) were used to predict SMFI and showed that dairy Ca was positively associated with muscle densities of the calf ( P ≤ 0.01, partial r (ρ)=0.185, β=0.216) and thigh ( P ≤ 0.05, ρ=0.135, β=0.157 ). Dairy VitD was independently associated with higher muscle densities of the calf (P≤ 0.01, ρ=0.183, β=0.194) and thigh ( P ≤ 0.05, ρ=0.159, β=0.168). CONCLUSION Lower dairy consumption is associated with increased SMFI in young girls. Grant Funding Source : NIH: HD050775