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Dietary protein and risk of elevated blood pressure in adolescent girls
Author(s) -
Buendia Justin G,
Hasnain Syed R,
Singer Martha R,
Moore Lynn L
Publication year - 2012
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.26.1_supplement.119.7
Subject(s) - medicine , confounding , demography , logistic regression , menarche , blood pressure , body mass index , zoology , biology , sociology
The prevalence of elevated blood pressure (EBP) has risen steadily for U.S. adults and children during the past 20 years. The goal of this study is to estimate the effect of dietary protein on adolescent blood pressure. Ten years of follow‐up data from 2379 girls in the National Growth and Health Study ages 9–10 years at baseline were used. Eight sets of 3‐day diet records were collected during the study. BP was measured 3–4 times at each annual visit. Outcomes of interest to these analyses include mean SBP, DBP and risk of EBP in late adolescence (mean age=18.3 years). Analysis of covariance and multiple logistic regression models were used to control for potential confounding by age, race, SES, height, physical activity, age at menarche, and TV/video viewing time. Adjusted mean SBP and DBP levels declined linearly with increasing quintiles of protein intake (SBP: 111.8, 109.7, 108.5, 107.7, 107.4 mmHg; DBP: 67.2, 65.8, 65.3, 64.5, 64.6 mmHg, respectively, for quintiles 1–5; p‐trend<0.0001 for both). Girls in the lowest quintile of intake (<1.0 g•kg body weight −1 •day −1 ) vs. the highest quintile (>1.7 g•kg body weight −1 •day −1 ) were 3.3 times as likely to develop EBP in late adolescence (95% CI: 2.1–5.0). These results were largely attenuated by inclusion of BMI in the models. Dietary protein intake above the current RDA had strong beneficial effects on adolescent BP resulting from its intermediate effects on body composition. Grant Funding Source : NIDDK and Small Grants