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Sex differences in bone mineral density after resistance training in growing rats
Author(s) -
Joo Woojin,
Singh Harpreet,
Ahles Cammie P,
Colazas William,
Lee Lucy,
Lee Yvonne,
Jaque S Victoria,
Sumida Ken D
Publication year - 2012
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.26.1_supplement.1142.50
Subject(s) - bone mineral , medicine , resistance training , statistical significance , tibia , strength training , endocrinology , osteoporosis , physical therapy , surgery
The purpose of this study was to determine if there was a sex difference in the resistance training‐induced elevation in bone mineral density (BMD) during the growth period in rats. Sixteen male and 16 female rats (~8wks old) were randomly divided into Control (MC=8, FC=8), and resistance trained (RT) groups (M‐RT= 8, F‐RT=8). The RT groups were conditioned to climb a vertical ladder 4 consecutive times (per exercise session) with weights appended to their tail 3 days/wk for a total of 6 wks. After 6 wks, left tibial BMD (in g/cm 2 ) was significantly greater for M‐RT (0.240 ± 0.005) compared to MC (0.211 ± 0.005). Further, bone strength (force to failure in Newtons) from the right tibia was significantly greater for M‐RT (144.4 ± 8.0) compared to MC (118.3 ± 2.7). In contrast, while the BMD for F‐RT (0.226 ± 0.006) was elevated compared to FC (0.214 ± 0.005), statistical significance was not achieved ( P =0.09) whereas bone strength was significantly greater ( P =0.04) for F‐RT (97.4 ± 3.5) compared to FC (82.3 ± 3.1). While the impact of resistance training demonstrated anticipated trends for BMD and bone strength among males and females, the training‐induced elevations were greater for M‐RT compared to F‐RT. The results indicate that the resistance training program was more effective for elevating BMD and bone strength in males compared to females during the growth period in rats.