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Bone metabolic markers and BMD after 10 weeks upper‐body resistance training in premenopausal women
Author(s) -
Quezada Lorena,
Liang Michael T.C.,
Sokmen Bulent,
Spalding Thomas W
Publication year - 2012
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.26.1_supplement.1142.48
Subject(s) - medicine , wrist , bone remodeling , osteocalcin , heel , n terminal telopeptide , ulna , bone resorption , resistance training , bone mineral , endocrinology , osteoporosis , alkaline phosphatase , surgery , anatomy , chemistry , biochemistry , enzyme
The aim of this study was to determine the effects of a 10‐week upper body resistance training (UBRT) on bone turnover markers (BTM) and site‐specific BMD in the wrist and distal ½ of the ulna and radius in untrained healthy premenopausal women. Twenty‐eight healthy subjects (age=22.1±1.8 yr) were randomly assigned to UBRT (UT, n = 12) or no training control (CON, n = 8) group. The following outcome variables were measured before and after 10 weeks of resistance training: 1) bone formation biomarker, osteocalcin (OC), and bone resorption biomarker, tartrate‐resistant acid phosphatase isoform 5b (TRACP5b), 2) BMD in the wrist, distal ½ of the ulna and radius, and heel, 3) isokinetic strength of the elbow and knee extensors and flexors, 4) arm extensors and flexors, and 5) maximal number of push‐ups. No significant group differences were observed for BTM (mean±SE, OC: 14.5±0.8 vs. 14.7±0.4 ng/ml and TRACP5b: 2.69±0.36 vs. 2.60±0.37 U/L, both p>0.05), and wrist BMD (0.487±0.01 vs. 0.444±0.01 g/cm2, p>0.05). Compared to baseline values, 1RM chest press and lateral pull‐downs increased 24% and 16%, respectively, and number of push‐ups increased 111% (all p<0.05) in the UT, not the CON. We conclude that muscular strength can be induced with a 10‐week musculoskeletal loading using resistance training, but not in bone metabolic markers and BMD in the wrist and distal ½ of the ulna and radius in untrained premenopausal women.