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Effects of physical exercise and taurine supplementation on cardio‐metabolic risk factors in high caloric‐fed rats
Author(s) -
Moraes Camila,
Rosini Tiago Campos,
Freitas Ellen Cristini
Publication year - 2012
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.26.1_supplement.1142.41
Subject(s) - taurine , tbars , medicine , endocrinology , caloric theory , analysis of variance , treadmill , oxidative stress , chemistry , lipid peroxidation , biochemistry , amino acid
To evaluate the effects of exercise sessions, three times a week, and taurine supplementation on blood concentration of glucose, triglycerides and TBARS. Twenty male Wistar rats were divided: sedentary (SD); sedentary taking taurine (SD+TAU); trained (TR) and trained taking taurine (TR+TAU). Exercise training and taurine supplementation (drinking water at 2%) started after four weeks of high caloric diet consumption and was carried out for further five weeks. Animals exercised at a treadmill (20 m/min), 60 min, 3 days/week. Insulin tolerance test (ITT) was done and K ITT calculated. After an overnight fasting, rats were sacrificed and glucose, triglycerides, and TBARS concentrations were measured by commercial kits. Data were analyzed by two‐way ANOVA (p<0.05). Exercise protocol improved performance about 45% in booth trained groups. Exercise or taurine, per se , reduced triglycerides (40%,77% and 67% for SD+TAU, TR and TR+TAU, respectively) and augmented K ITT (16%,20% and 26% SD+TAU, TR and TR+TAU). TBARS was reduced only in SD+TAU (33%) and TRD+TAU (29%). None differences were seen on body weight and in blood glucose. In conclusion, taurine supplementation, as physical exercise 3 days a week, improves metabolic profile in high caloric fed‐rats, except for oxidative stress biomarker. Financial support: FAPESP