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Relations between iron status and cognitive measures in Indian adolescents
Author(s) -
Scott Samuel Pew,
Wenger Michael J.,
Murray-Kolb Laura E.,
Udipi Shobha A.,
Ghugre Padmini S.,
Boy Erick,
Haas Jere D.
Publication year - 2012
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.26.1_supplement.1031.12
Subject(s) - iron deficiency , cognition , ferritin , effects of sleep deprivation on cognitive performance , iron status , soluble transferrin receptor , population , medicine , psychology , pediatrics , audiology , anemia , environmental health , psychiatry
Iron deficiency (ID) is the most common nutrient deficiency, affecting an estimated 25% of the global population. However, the functional effects of ID in children between the ages of 12–16 years, a period of life during which behavior and cognition continue to develop, are largely understudied. In the current 7‐month double‐blind intervention, pearl millet biofortified with iron was tested for its efficacy to improve iron status in rural Maharashtrian children (n=247; 12–16 y; female=73, male=174). Here, we present analysis of baseline data. A random subsample (n=150) underwent testing of cognitive performance using 5 measures to evaluate simple reaction time, response inhibition, low‐ and high‐level attentional control, semantic memory, and recognition memory. Blood measures of iron status included hemoglobin, ferritin and transferrin receptor. Inflammation was assessed via C‐reactive protein and alpha‐1‐acid glycoprotein. Relations between iron status and performance on cognitive tasks were examined.