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Gender influences Metabolic Syndrome Criteria
Author(s) -
Aguilar David,
Barona Jacqueline,
Dugan Christine E,
Andersen Catherine J,
Blesso Christopher N,
Fernandez Maria Luz
Publication year - 2012
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.26.1_supplement.1014.5
Subject(s) - medicine , endocrinology , metabolic syndrome , waist , blood pressure , abdominal obesity , population , cholesterol , plasma glucose , obesity , insulin , environmental health
Metabolic syndrome (MetS) parameters were evaluated in sixty six participants (24 women and 42 men) to determine whether gender influences the inclusion criteria of MetS [waist circumference > 88 cm in women and > 102 cm in men; HDL cholesterol (HDL‐C) < 50 and < 40 mg/dL in women and men, respectively; plasma triglycerides (TG) > 150 mg/dL, blood pressure (BP) > 130/85 mm Hg and plasma glucose > 100 mg/dL]. The most prominent criteria in men for MetS classification was high systolic BP (80%), high TG (66%) and low HDL (38%). In women, the criteria were high WC (100%), low HDL (42%) and high plasma glucose (38%) Comparisons between gender indicated that women had higher HDL‐C (p< 0.05) while men had higher plasma TG, and systolic blood pressure (p< 0.05). In women, High WC was correlated with low HDL‐C (r = −0.520, p< 0.01) and high TG was correlated with elevated blood glucose (r= 0.406, p< 0.05). In men, high TG were correlated with low HDL‐C (r‐0.594, p< 0.05). These results indicate that WC, the most common inclusion criteria for women is associated with dysregulation of plasma lipids and glucose metabolism as a result of increased fat accumulation in the abdominal area. While in men the elevated plasma TG are associated with low HDL suggesting that lipid abnormalities that place individuals at MetS classification are more common in this male population.