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Higher energy expenditure but lower physical activity levels with increasing obesity
Author(s) -
DeLany James P,
Jakicic John M,
Kelley David E,
Hames Kazanna C,
Goodpaster Bret H
Publication year - 2012
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.26.1_supplement.1012.4
Subject(s) - obesity , physical activity , energy expenditure , medicine , doubly labeled water , commonwealth , lean body mass , resting energy expenditure , sedentary lifestyle , endocrinology , body weight , physical therapy , political science , law
The role that physical activity plays in obesity is not clear. Furthermore, there is a dearth of information regarding the contribution of energy expenditure (EE) to severe obesity. We measured EE in 177 individuals ranging from lean to severely obese. We measured total EE (TEE) by doubly labeled water, resting EE (REE) by indirect calorimetry, activity EE (AEE) by difference, and time spent in physical activity by multisensor activity monitors. All components of EE were elevated in obese individuals. After adjusting for differences in body composition, REE was similar in all groups. The strong relationship observed between AEE (and TEE) and body weight in the lean was blunted in the obese, particularly the Class III obese. Obese individuals spent less time engaged in physical activity (2.7 ± 1.3 vs.1.2 ± 1.0 hr/d in lean and Class III), and more time in sedentary behaviors (20.7 ± 1.5 vs. 21.8 ± 1.1 hr/d in lean and Class III). In conclusion, although obese individuals have elevated EE, adjusted REE is normal. Using a combination of state of the art techniques allowed us to demonstrate that obese have a lower TEE and AEE in relation to their increased body weight, which can be explained by less time spent in physical activity and more time in sedentary behaviors than lean individuals. These findings support a role for low physical activity in obesity, and suggest that inactivity is a target for prevention. Funded by Commonwealth of Pennsylvania Department of Health