Premium
The Local Prevalence of Vitamin D Deficiency or Insufficiency in Southeast Michigan
Author(s) -
Duanmu Zhengbo,
Shah Rita P,
Reddy Vishnuvardhan,
Shah Alka Y,
Marella Basil J,
Gupta Neelum,
Roth Frank,
Knapp Mary J,
Shah Dinesh M
Publication year - 2012
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.26.1_supplement.1008.1
Subject(s) - vitamin d deficiency , medicine , vitamin d and neurology , population , cohort , vitamin , retrospective cohort study , cohort study , gastroenterology , physiology , environmental health
Serum 25(OH) vitamin D level is critical for optimal health. Vitamin D deficiency is associated with skeletal abnormalities as well as numerous other health issues. The objective of this study was to evaluate by age and gender the local prevalence of vitamin D deficiency and insufficiency in a population from an area of Northern latitude (Southeast Michigan). This was a retrospective cohort study of 1016 patients with serum vitamin D measurements from December 2010 to June 2011. Vitamin D level were normal in 323 patients (31.8%), insufficient in 337 patients (33.2%) and deficient in 356 patients (35.0%). The average vitamin D levels in both male and female were below normal (24.8±13.2 and 27.5±13.2 respectively). Contrary to other reports, our results showed vitamin D levels increased with age. For patients age >60, 30–59, and <30, the average 25(OH) D levels declined considerably from 28.9±13.9, 22.9±11.5, to 17.6±7.6, respectively (P<0.001 among each group). Consistent with previous investigations, these findings suggest a high prevalence of vitamin D deficiency and insufficiency. The serum 25(OH) D levels were markedly lower in males compared to those in females. Surprisingly, serum 25(OH) D levels were lowest in the younger population. Current recommendations for vitamin D supplementation may need to be adjusted accordingly based on these results. Supported by Michigan Physicians Group internal funding.