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Thermoregulatory responses are enhanced by glucose ingestion compared with fructose ingestion during passive heating in men
Author(s) -
SUZUKI AKINA,
OKAZAKI KAZUNOBU,
IMAI DAIKI,
TAKEDA RYOSUKE,
NAGHAVI NOOSHIN,
MATSUMURA SHINYA,
KAWABATA TAKASHI,
MIYAGAWA TOSHIAKI
Publication year - 2011
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.25.1_supplement.lb562
Subject(s) - ingestion , medicine , fructose , endocrinology , insulin , chemistry , thermoregulation , vasodilation , plasma osmolality , sweat , plasma volume , food science , vasopressin
Acute hyperglycemia attenuates the rise in esophageal temperatures (T es ) during exercise in the heat. We assessed the effects of acute hyperglycemia and insulin secretion on thermoregulatory responses. Methods Ten healthy young men performed two trials in a sitting position in an artificial climate chamber (28°C of T a , 40% of RH). After 10 min baseline measurement, subjects drank glucose (GLU; water 300 ml + glucose 75 g) or fructose solution (FRU; water 300 ml + fructose 75 g), then 20 min after, they were heated passively (lower leg immersion in 42°C water) for 60 min. During experiment, plasma glucose concentration ([Glu] p ), plasma osmolality (Posm), insulin and catecholamine concentrations, T es and skin temperatures (T sk ), sweat rate (SR) and cutaneous vascular conductance (CVC) at forearm and chest were measured. Results [Glu] p was higher in GLU than FRU without significant differences in Posm and changes in plasma volume during passive heating. T es threshold for sweating and cutaneous vasodilation at both sites were significantly lower in GLU than FRU. The sensitivity of increases in SR at chest at a given increase in T es was significantly higher in GLU and FRU. Increase in T es at the end of passive heating was lower in GLU than FRU. Conclusion Thermoregulatory responses during passive heating at rest were enhanced by glucose compared with fructose ingestion, which may be associated with insulin secretion.