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MEDITERRANEAN DIET ADHERENCE. WHICH RELATIONSHIP WITH OBESITY AND INSULIN RESISTANCE
Author(s) -
Trovato Guglielmo M.,
Catalano Daniela,
Pirri Clara,
Trovato Francesca M,
Pennisi Alessia,
Puglisi Claudia,
Martines G. Fabio
Publication year - 2011
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.25.1_supplement.lb299
Subject(s) - medicine , insulin resistance , mediterranean diet , overweight , obesity , homeostatic model assessment , gastroenterology , endocrinology
Relationship of Adherence to Mediterranean Diet, insulin sensitivity and obesity is controversial. Adherence to this dietary profile was associated with reduced weight gain, so that this dietary pattern could be recommended to slow down age‐related weight gain, but others report increased Insulin Resistance (IR). Methods 187 consecutive non‐diabetic overweight‐obese patients (F 114, M 73, years 47,17±13,95, BMI 32,72±5,79), no/low alcohol habits (< 20 ml/day), were referred to our Day‐Hospital‐Clinic for dietary counseling. Insulin Resistance by HOMA (Homeostasis‐Model‐Assessment‐IR) and the Adherence Mediterranean Diet Score (AMDS: range: 0–55) were assessed. Dietary data were collected by monthly dietary recall; Dietosystem® diet prescriptions were provided. Results No correlation between AMDS vs. BMI (r= −0,028; p: NS ) whereas inverse correlation between AMDS and HOMA (r= −0,306; p: <0,0001) were found. By Odds Ratio the risk for IR (HOMA≥1.7) is increased by more severe obesity (OR: 3,002; CI 1,509–5,972) and decreased by 75% by greater AMDS (OR: 0,266; CI: 0,136–0,523). Multiple Linear Regression model (p< 0,0001) explains by AMDS, BMI and HDL 25,7 % of variance to HOMA. Conclusion Mediterranean Diet Adherence in obesity is associated with lower prevalence and severity of IR, despite the association with greater BMI. This dietary pattern might be advised for improving insulin sensitivity.